ANTI AGING

Botox Treatment

Botox treatment functions by stopping the receptors (acetylcholine) in the muscles of your face neck or wherever the injections are given. The acetylcholine is introduced into your tissues, when the nerve sends alerts for the muscles to shift or contract. This generally happens in cases where muscle mass has no clue if it's really supposed to go, thus becoming paralysed. The sensation of numbness remains only for a short period of time.

The blockade made by acetylcholine is permanent and begins inside 2 days. The medical outcomes from the injection come to be apparent within 5 to 8 days. After 3 to 6 months, the muscle starts developing new receptors and might contract all over again.

If the body part where the injections are supposed to be given is not big, then it becomes important to send out electric impulses to make sure that the right muscles are acquiring the injection. The best cosmetic surgeon uses an incredibly small needle to perform Botox treatment. Some people may feel slight or short-term pain in the course of the Botox treatment even when it is being performed by the best cosmetic surgeon. Once the Botox treatment is completed, the injected drug will not trigger any form of irritation.

The main work of Botulinum toxin is to smooth the wrinkles and fine lines that may appear due to various types of aging factors. With age, skin loses its elasticity and permanent lines appear in areas like eyes, forehead, mouth, and chin, in most cases all over the face and neck. When a person smiles these fine lines and wrinkles become more visible. Botox treatment softens these lines though it may not quite be successful in eliminating these lines permanently.

Botox treatment is a lot more than beauty therapy and is beneficial in the treatment of many other health issues like eye squints, chronic headaches and too much sweating. You will also find other ailments that botulinum toxin can proficiently deal with such as migraines, incontinence, severe neck and shoulder muscle spasms.

Reasons To Use Anti-Aging Pills

Who wants to grow old? No doubt you are as old as you feel, but you can never beat time. It is that one thing, which you can't run away from. No matter how far you try to go from it, you can never win the race against time. Yet, I don't advice you to surrender!

As you grow older, or get into the phase of growing older post 40, the whiplashes of time are visible on your face. This is where anti-aging creams and pills come into the picture. If you take my advice, I always suggest people to use pills, rather than using creams.

Following are the top five reasons to use such pills:

1. To fight against the process of aging - I am sure you don't want to look old, or at least older than your age. Due to stress, pollution and a lot of other factors, you, at times, look older than your exact age. That's why a lot of people prefer medicines to look younger and better.

1. To complement your figure or physique - If you believe in maintaining yourself, you surely want to look younger, fitter and cuter. To look appealing to others, you have got to consume something that helps you look younger.

1. To disallow any effect of time - If you want to get compliments from people, you have to find out a medicine that allows you to stop any effect of the passing time. No one should be able to guess your age, by looking at the wrinkles on your face or skin.

1. To imitate your favorite star - There are a lot of fans, who imitate their favorite stars or celebrities; if you are one of them and you want to imitate your favorite celebrity, it is essential for you to find out if he or she is on anti-aging tablets or not. Most of them use such things to keep themselves presentable enough to the eyes of their fans.

1. To impress the others around you - Who doesn't wish to get complimented from people? Has any stranger ever approached you and said that you look wonderful? If no one has done this for you, then he surely will, if you start using a tablet that allows you to pause time for a few years and make you look healthier and lovelier. Men, especially, prefer women, who look younger than their actual age.

Go ahead and find some of the most popular anti-aging medicines to relieve yourself from the stress of growing old!

 

Cellular Death Approach to Anti-Aging Treatment

Modern anti-aging treatment is built on a common base of knowledge that I will quickly review. Biochemistry and molecular biology tell us there are many types of chemical reactions going on in the human body. We know that it is the genetic information programmed inside our cellular DNA that defines what reactions occur. Genetic information, expressed in regulated ways, builds the body's proteins and enzymes, and controls how enzymes carry out the cell's biochemical reactions.

This information, contained in the DNA of our genome, consists of many thousands of long, often repetitive, sequences of base pairs that are built up from four basic nucleotides. Human genome mapping has shown there are over 3 billion base pairs in our DNA. It is estimated they contain some 20,000 protein-coding genes. All body functions are controlled by the expression of the genes in our genome. The mechanisms controlling the aging process are believed to be programmed into our DNA but only a fraction of the biochemical reactions related to the aging process have been looked at in any detail. Cellular aging is a very complex process and many of its low level operating details have yet to be discovered.

Anti-aging theory has consolidated itself along two lines of thought: the programmed cellular death theory and the cellular damages theory. The programmed death theory focuses on the root causes of aging. The cellular damages theory looks at the visible aspects of aging; i.e. the symptoms of aging. Both theories are correct and often overlap. Both theories are developing rapidly as anti-aging research uncovers more details. As works in progress these theories may take years to complete. This broad characterization also applies to the currently available types of anti-aging treatments.

The programmed death theory of aging suggests that biological aging is a programmed process controlled by many life span regulatory mechanisms. They manifest themselves through gene expression. Gene expression also controls body processes such as our body maintenance (hormones, homeostatic signaling etc.) and repair mechanisms. With increasing age the efficiency of all such regulation declines. Programmed cellular death researchers want to understand which regulatory mechanisms are directly related to aging, and how to affect or improve them. Many ideas are being pursued but one key area of focus is on slowing or stopping telomere shortening. This is considered to be a major cause of aging.

With the exception of the germ cells that produce ova and spermatozoa, most dividing human cell types can only divide about 50 to 80 times (also called the Hayflick limit or biological death clock). This is a direct consequence of all cell types having fixed length telomere chains at the ends of their chromosomes. This is true for all animal (Eukaryotic) cells. Telomeres play a vital role in cell division. In very young adults telomere chains are about 8,000 base pairs long. Each time a cell divides its telomere chain loses about 50 to 100 base pairs. Eventually this shortening process distorts the telomere chain's shape and it becomes dysfunctional. Cell division is then no longer possible.

Telomerase, the enzyme that builds the fixed length telomere chains, is normally only active in young undifferentiated embryonic cells. Through the process of differentiation these cells eventually form the specialized cells from which of all our organs and tissues are made of. After a cell is specialized telomerase activity stops. Normal adult human tissues have little or no detectable telomerase activity. Why? A limited length telomere chain maintains chromosomal integrity. This preserves the species more than the individual.

During the first months of development embryonic cells organize into about 100 distinct specialized cell lines. Each cell line (and the organs they make up) has a different Hayflick limit. Some cell lines are more vulnerable to the effects of aging than others. In the heart and parts of the brain cell loss is not replenished. With advancing age such tissues start to fail. In other tissues damaged cells die off and are replaced by new cells that have shorter telomere chains. Cell division itself only causes about 20 telomere base pairs to be lost. The rest of the telomere shortening is believed to be due to free radical damage.

This limit on cell division is the reason why efficient cell repair can't go on indefinitely. When we are 20 to 35 years of age our cells can renew themselves almost perfectly. One study found that at the age 20 the average length of telomere chains in white blood cells is about 7,500 base pairs. In humans, skeletal muscle telomere chain lengths remain more or less constant from the early twenties to mid seventies. By the age of 80 the average telomere length decreases to about 6,000 base pairs. Different studies have different estimates of how telomere length varies with age but the consensus is that between the age of 20 and 80 the length of the telomere chain decreases by 1000 to 1500 base pairs. Afterwards, as telomere lengths shorten even more, signs of severe aging begin to appear.

There are genetic variations in human telomerase. Long lived Ashkenazi Jews are said to have a more active form of telomerase and longer than normal telomere chains. Many other genetic differences (ex.: efficiency of DNA repair, antioxidant enzymes, and rates of free radical production) affect how quickly one ages. Statistics suggest that having shorter telomeres increases your chance of dying. People whose telomeres are 10% shorter than average, and people whose telomeres are 10% longer than average die at different rates. Those with the shorter telomeres die at a rate that is 1.4 greater than those with the longer telomeres.

Many advances in telomerase based anti-aging treatments have been documented. I only have room to mention a few of them.

- Telomerase has been used successfully to lengthen the life of certain mice by up to 24%.

- In humans, gene therapy using telomerase has been used to treat myocardial infarction and several other conditions.

- Telomerase related, mTERT, treatment has successfully rejuvenated many different cell lines.

In one particularly important example researchers using synthetic telomerase that encoded to a telomere-extending protein, have extended the telomere chain lengths of cultured human skin and muscle cells by up to 1000 base pairs. This is a 10%+ extension of telomere chain length. The treated cells then showed signs of being much younger than the untreated cells. After the treatments these cells behaved normally, losing a part of their telomere chain after each division.

The implications of successfully applying such techniques in humans are staggering. If telomere length is a primary cause of normal aging, then, using the telomere length numbers previously mentioned, it might be possible to double the healthy time period during which telomere chain lengths are constant; i.e. from the range of 23 to 74 years to an extended range of 23 to 120 or more years. Of course this is too optimistic because it is known that in vitro cultured cells are able to divide a larger number of times than cells in the human body but it is reasonable to expect some improvement (not 50 years but say 25 years).

We know that telomerase based treatments are not the final answer to anti-aging but there is no doubt that they can by increase the Hayflick limit, extend or even immortalize the lifespan of many cell types. It remains to be seen if this can be done safely done in humans.

Telomerase based treatments are only a partial answer to anti-aging. Please carefully research any anti-aging supplements based on this line of treatment. Through my articles and website I want to help you maintain your good health for the next 10 to 25 years. My hope is that within time period the fruits of anti-aging research will become available to everyone.

 

Human Growth Hormone Retard Aging?

As we get older our skin grows thinner, we lose muscle and bone, and gain fat. These changes are part of the aging process.

A study conducted in 1990 by Dr Daniel Rudman, which was published in the New England Journal of Medicine, investigated the effects of human growth hormone (HGH) on healthy adults. Twelve men (aged 61 to 81) received injections of human growth hormone for six months.

The twelve men developed thicker skin, bigger muscles and denser bones, and lost fat. On average they experienced:

• 7.1% increase in the thickness of their skins
• 8.8% rise in lean body mass
• 1.6% increase in bone density, and
• 14.4% decrease in fat tissue

Rudman, it seems, had 'reversed aging'.

So what is human growth hormone?

Human Growth Hormone (HGH)

Human growth hormone (HGH) is produced in your pituitary gland.

As its name implies, this hormone is responsible for cell growth and regeneration. Indeed increasing muscle mass and bone density are impossible without HGH.

HGH also plays a major role in maintaining the health of all human tissue, including that of the brain and other vital organs.

When secreted by the pituitary gland, HGH remains active in the bloodstream for only a minute or so, just long enough for the liver to convert it into growth factors.

The most crucial growth factor is insulin-like growth factor-1 (IGF-1) which has a host of anabolic properties, ie it can synthesize molecules in metabolism.

These anabolic properties mean that HGH promotes and increases the synthesis of new protein tissues, such as in muscle recovery or repair. This is the way new muscle is built.

Recent research suggests that HGH is also involved in the metabolism of body fat and its conversion into energy. It improves the sleeping pattern, making better REM-stage sleep.

It also builds stronger bones, improves immune function, decreases cholesterol and improves vision. In addition, it increases the sex drive, helps maintain mental acuity and engenders a general sense of well-being.

There's no doubt that HGH slows the progression of age-related degenerative diseases. This suggests that people who age prematurely may have a HGH deficiency.

Indeed your body does produce copious amounts of HGH when you are a child but the output from your pituitary gland declines as you get older. After the age of 30 it reduces by about 25% every decade or so, so by the time you hit 60 you are probably operating at 25% of original capacity.

Thus, among the elderly, a deficiency in HGH is highly likely. Finding out is just a matter of a simple blood test following an overnight fast.

So how can you stimulate the release of more HGH?

HGH Injections

In most countries injections of HGH are tightly controlled and can only be administered when prescribed by a doctor. There are good reasons for these restrictions.

If you overdose on human growth hormone you could end up with acromegaly in which your bones, face and intestines grow along with the growth in your muscles. Not a pleasant experience!

There is no need however to go for HGH injections. If you discover you are HGH deficient you can up your secretion of HGH with:

• training
• rest
• nutrition

Purposeful training

Intense workouts, energy-consuming events, and long periods of physical exhaustion are the keys to stimulating the release of more HGH. This is the most potent kind of GH release, as it's targeted to meet the demands of the muscles you are using.

The basic rule of thumb is never to train for more than 45 minutes because that's the point where production of HGH begins to taper off and the production of cortisol starts.

Adequate rest

Three-quarters of your total daily output of HGH is produced while sleeping and most of that during REM (deep) sleep. So getting a good's night sleep is imperative for boosting HGH.

The HGH produced in this way is not as potent as the other kinds, because it is produced in response to a need to sleep to allow your energy to be refilled for the next day, rather than a need for extra energy. But, without the HGH produced through proper rest, other sources of HGH may not be used as efficiently as they are.

Getting 8 to 10 hours of sleep every night is a sacrifice you have to make if you want to regain some of your youthful tone and vigour.

You also need to keep regular sleeping hours because this promotes more REM cycles which results in an increased output of HGH.

Nutrition

Protein is needed to build your muscles, so eat more protein.

In this regard, ingesting a range of amino acids in a protein shake 45 minutes before a workout could be very useful as most amino acids can produce HGH synergistically. Ensure that the shake includes arginine, glutamine and taurine which are considered the most effective in producing HGH.

Other dietary sources of nutrients to promote HGH are Vitamins C, A, B3, B5 and B12, chromium and zinc, and most antioxidants. Many of these are available in your daily multi-vitamin.

 

Key Ideas of the Cellular Damages Theory of Aging (CDTA)

Part one of this four part article discussed the programmed cellular death theory of aging. The main topic of this article is the cellular damages theory of aging (CDTA). The CDTA approach to anti-aging treatment is to understand and treat the various types of cellular damage associated with aging and closely related diseases. Per this theory the best path to effective anti-aging treatment is to attack the symptoms of aging. Treating symptoms is a successful and useful technique that most doctors use. If the root cause of a medical problem is unknown or too difficult to uncover, doctors will fall-back to treating the symptoms of the problem. The problem itself may or may not go away but good treatment of its symptoms will allow the problem to remain hidden indefinitely. Many of the root causes of aging are not yet understood well enough to be treated directly. This is reflected in a growing trend in anti-aging medicine. Doctors are becoming specialists in treating the specific symptoms of aging but not aging itself. This approach to anti-aging is definitely not the final answer but it is the best that we can do for now. It can add many more productive years to one's life.

Everyone is constantly exposed to various types of cellular stress. Cellular DNA damage occurs at a rate of many thousands of molecular level disruptions per day. DNA and other repair mechanisms try to correct this damage and the process of apoptosis removes the most badly damaged cells. Healthy cells, when signaled through mitogenic stimulation from neighboring cells, undergo mitosis and divide to replace damaged cells. The process is good but imperfect. Fatal and non-fatal errors can and do occur during many phases of the repair and reproduction processes. In addition to controlling cell division, human cells have evolved complex systems of inter cellular signaling that they rely on to function normally. These signaling systems have to be operating correctly or the cell will act as if it is no longer needed and commit suicide through apoptosis. This is an area of study for CDTA because many cellular regulatory mechanisms, including cellular signaling, weaken and start failing as old age begins manifesting itself.

Other specific types of cellular damages that CDTA studies include: various types of cellular mutations, cross linking and glycation, free radical damage, and the accumulation of cellular waste products. CDTA also tries prevent cellular damages caused by inflammation and oxidative stress. It has been shown that these factors can cause cellular aging by permanently stopping cell reproduction without shortening the length of cellular telomere chains. Most of the types cellular damages described above accumulate with age. Their effects may not be visible when you are young but their net result is that your cells are continuously aging.

Included in CDTA is the free radical theory of aging (FRTA) and its derivative theory, the mitochondrial theory of aging. In simple general terms these theories say is that many of the symptoms of aging are due to uncorrected accumulation of cellular damage caused by free radicals. The key point that free radical damages accumulate with age is now a well accepted idea. Free radicals (highly reactive ionized molecules) are always present and always cause molecular damage. Free radicals are continuously being produced and removed by the human body. Environmental factors (pollution, radiation, cigarette smoke, herbicides etc.) can increase free radical products in the body. Within the body free radical species such as reactive oxygen species (ROS) and reactive nitrogen species (RNS) are by-products of the normal cellular redox process. They are simultaneously both essential and harmful to cellular life. Human tissue cells have to maintain a delicate working balance between these opposite effects. This homeostatic balance is also referred to as the "redox balance".

There are two popular CDTA anti-aging treatment approaches to slowing the cellular damage caused by free radicals. They are championed by different, somewhat conflicting, camps of people. The smaller camp wants to stimulate the body's own antioxidant systems. The larger group advocates using significant amounts of external antioxidants such as vitamin C, E and other supplements. I will discuss the differences these groups have in their approaches to anti-aging in my next article but for now a little more background on free radicals and antioxidants might be useful.

Concentrations of free radicals in the body may rise to dangerous levels if they are not neutralized quickly enough. High free radical levels increase oxidative stress in the body which then starts damaging cellular molecules. This type of biochemical stress helps cause many or even most diseases. A very short and incomplete list of such diseases includes: "aging", chronic and degenerative illness such as autoimmune disorders, cancer, cardiovascular and neurodegenerative diseases (ex. Alzheimer's Disease), diabetes, cataracts, and rheumatoid arthritis. Antioxidants are continually being used and replenished to keep free radical concentrations within manageable limits. Both internal (endogenous) and externally (exogenous) obtained antioxidants neutralize free radicals and help maintain the radox balance.

Mammalian cells have internal enzymatic antioxidants (Superoxide Dismutase (SOD), Glutathione Peroxidase, Glutathione reductase, various Catalases, and other antioxidants) that form the first line of defense against free radical damage. These enzyme systems require externally provided (diet and supplements) nutritional minerals such as selenium, iron, copper, zinc, and manganese to act as cofactors for optimum catalytic activity. These defenses against free radicals consist of several sensing and signaling mechanisms that activate and deactivate the production of internal antioxidants. One such mechanism is the Nrf2 protein activation system. High levels of free radicals will activate the normally latent Nrf2 protein. Once released, Nrf2 activates the antioxidant Response Element (ARE), also called hARE (Human Antioxidant Response Element). This master regulator of the cellular antioxidant system then increases the production many natural antioxidants. A variety of foods, taken in very modest amounts, can activate Nrf2 and greatly increase the production of natural antioxidants. This includes foods such as: green tea, turmeric, and red wine. Other known Nrf2 activators include lowered oxygen content (hypoxia) and food deprivation (calorie reduction). CDTA experts generally agree with the above descriptions but they disagree on how best to apply this information for anti-aging therapy. The next article in this series will discuss the approaches CDTA has to anti-aging.

As a former engineer I have a strong affinity to all sciences including biology. My interests include following advances in the fields of anti-aging, health and nutrition. Rapid advances in these areas will vanquish the disease we call aging. Through my articles and website I want to help you maintain your good health for the next 10 to 25 years. I believe this can be done by a daily program that includes moderate exercise, a healthy diet that includes vitamins and anti-aging supplements, and taking advantage of any advances in anti-aging and nutrition research. My hope is that within the next 25 years or less, the fruits of anti-aging research will become available to everyone.

The Cellular Damages Theory of Aging (CDTA) Approach to Anti-Aging Treatment

CDTA supporters of stimulating the natural production of antioxidants claim that natural antioxidants provide better protection against the damaging effects of free radicals than taking antioxidant supplements. One concern this group has is that the triggering mechanisms for the production of natural antioxidants can be desensitized by the over use of antioxidant supplements. The belief here is that a continuous production of natural antioxidants brought on by very mild activation of the Nrf2 protein is the healthiest possible state for human body. Anything that disrupts this does more harm than good. They also claim that the natural antioxidant production may be disrupted by taking too much of known Nrf2 activators such as curcumin or resveratrol. Some supporters in this group believe that current antioxidant over-supplementation has already created serious health issues.

The main proponents of CDTA support the idea of taking significant amounts of readily available external antioxidants such as vitamin C, E, and other supplements. Many of them recommend taking one or more grams of Vitamin C daily. They believe this can safely reduce the amount of cellular damage free radicals generate. The good news is that some research actually does support this claim. The not so good news is that the concerns of the pro natural antioxidant camp are not being taken seriously. It is also true that, by focusing on a few well known antioxidants, too little attention is being paid to the role antioxidants play in the body.

Humans utilize numerous (1000s) types of antioxidants and their variants. Each antioxidant's biochemical reactions with different kinds of free radicals are unique. A few antioxidants, such as Vitamin A, C, and E are popular and are well known. Most others such as Uric acid, best known for its association with gout, are much less well known but are equally important. Using this antioxidant as an example, Uric acid, which in humans happens to have the largest blood concentration of all antioxidants, is responsible for over half of the antioxidant capacity of human blood serum. Uric acid can reduce oxidative stress caused by high-altitude hypoxia. A great many antioxidants that counteract free radicals also inhibit viruses and bacteria. Most of this CDTA related antioxidant research is only reported in technical journals but the research itself suggests that lots of interesting anti-aging tidbits being put on the shelf for future study or are under reported.

The human body has several enzyme systems that fight free radicals by using antioxidants (vitamins A, C, E, and the mineral selenium) we can only get through our diets and/or by supplements. Vitamins A, C, and E are also essential nutrients. Dietary deficiencies of these antioxidants can cause specific diseases and possibly lead to other chronic and/or degenerative health problems. A Beta-carotene (vitamin A) deficiency can cause night blindness. Vitamin C deficiency can cause scurvy. Vitamin E deficiency can causes nerve conduction problems. In the U.S. a diet rich enough in fruits and vegetables (6 to 8 daily servings) can prevent such deficiencies and is highly recommended. In reality such an ideal diet may be difficult to maintain. This presents a strong argument for supporting the use of at least a few antioxidant supplements.

Bickering among advocates of CDTA has left us with several pressing unanswered questions. Should we rely on naturally produced antioxidants and limit our use of external antioxidant supplements? What are the correct antioxidant supplement dosages you need to slow down the aging process? At the moment there are no agreed upon standards to go by.

CDTA tells us cellular damage is cumulative. This may mean the real answers are relative; i.e. they will vary depending on how old you are. It is a well established fact that the efficiency of many of the body's homeostatic mechanisms declines with age. If you are getting older, say over 60 years of age, your natural antioxidant defences are slowly weakening. How long can you rely on them to adequately protect you? The efficiency of the body's digestive absorption of many foods, including the trace minerals that the natural antioxidant systems require, slowly decreases with age. At a certain point in life an increase in antioxidant supplements and/or supplemental digestive enzymes may really be helpful. Several of the antioxidants produced in our body are becoming available in the supplement market.

The current interpretation of CDTA's vague approach to anti-aging is that to slow down the rate at which cellular damage accumulates you should increase your daily intake of dietary antioxidants (fruits and vegetables) and perhaps take some unspecified amount of various vitamins and anti-aging supplements. With increasing age you may need to increase your intake of vitamins and antioxidant supplements. Until the experts agree on supplement dosages you will have to diligently research any supplement you are interested in.

There are hundreds of health supplements available on the market. Many scientific studies on the benefits of any given health supplement are at odds with each other. Some claim taking supplements has benefits while others claim there are few or no benefits, or that supplements may even be harmful. The vitamin and anti-aging supplement business has become a 23 billion dollar industry that is not being regulated very well. This has allowed the market to become full of overpriced products that may have few real benefits. You need to be careful. In my next article I will wrap things up by summarizing the status of current approaches to anti-aging treatment.

As a former engineer I have a strong affinity to all sciences including biology.
My interests include following advances in anti-aging, health and nutrition. Rapid advances in these areas will vanquish the disease we call aging. Through my articles and website I want to help you maintain your good health for the next 10 to 25 years. My hope is that within time period the fruits of anti-aging research will become available to everyone.

Different Aging Rates in Men's and Wome

For years, practically everyone has known that men and women age differently. It has been common knowledge for several decades that men typically don't fare as well as women when it comes to getting older.

As a result, they're more likely to get serious diseases later in life and they are also more likely to pass away at a younger age. However, new research shows that the differences between men and women also exist in the brain. In fact, men and women's brains age at a far different rate. There are several key differences that should be explored more in-depth.

Perhaps the most important thing is that men's brains have a tendency to be better developed when it comes to things like muscle coordination and movement. For example, they might be able to balance on one foot better or they may be more adept at a particular sport.

They also might have better dexterity and hand eye coordination than many women. With that being said, their brains also deteriorate at a much faster rate when it comes to things like movement, balance and coordination. Regardless of how athletic a man might be in his prime, there is every chance that he will be far less capable as he gets older.

In addition, the part of the brain that processes emotions has a tendency to age much more quickly in men than it does in women. What does this mean for someone in a realistic sense? It often means that men are simply not capable of handling emotions in the same way that they have always done. Even someone who has always been very mature about his emotions and has managed to keep them in check during difficult circumstances may find himself exploding in rage or crying uncontrollably for no apparent reason. This is not necessarily the fault of the individual, but more likely because of the deterioration within the brain.

As if that were not enough, women's brains age more slowly when it comes to the part of the brain that is responsible for memory. This basically means that women can usually remember better than men as they get older. Almost all men have significant deterioration in the part of the brain that is responsible for memory that is directly associated with advancing age. This might even make them susceptible to dementia and other memory related diseases.

One of the more interesting possibilities is that lifestyle could be hugely responsible for these differences. Scientists do not yet know if the differences between men and women's brains is hardwired or if it is a direct result of the lifestyle that each vendor chooses. Without a doubt, a great deal more research will have to be conducted before any definitive answers can be obtained concerning this particular question.

One thing is certain, there are a lot of differences between men's and women's brains. As a result, more information can be found about these differences that can help people relate to each other in all aspects of their lives, especially as they grow older together. This research essentially represents the tip of the iceberg and there is much more to be learned in the future.

Anti Aging Supplements

It's no surprise that a lot of people want to look and feel younger than their age. So many anti aging products promise to make people look youthful. However, most of these products are for external use only, thus you only get limited benefits.

In order to truly slow down the biological clock, you need to be healthy from within. For this reason, anti aging supplements such as Resveratrol Ultima are produced. Continue reading to find out how herbal supplements can make you look younger than your age.

Fight signs of aging

As we grow older, we tend to show signs of aging such as sagging skin, thin hair and overall body weakness. However, with the right herbal preparation, we can help to delay these signs significantly in a safe and natural way. No need to go for expensive procedures to delay aging. Instead, focus on helping your body stay strong from within with herbs.

Clean and detoxify

As time goes on, many toxic elements accumulate in our body. They can come from food, pollution around us as well as from the body's inability to get rid of waste properly. If we allow these harmful things to stay in our bodies then we can become sick.

Products such as Resveratrol Ultima help to clean and detoxify our bodies. With regular detoxification, our bodies are able to fight diseases better and become more stronger.

Provide energy

As we grow older, we tend to feel more weak and this can affect our daily lives significantly. However, herbal supplements can provide the necessary energy boost that we need to be able to go about our daily routine.

Quick results

With the right product, you can notice positive results in a short time. This is because the potent ingredients in herbal supplements work quickly and effectively. If you purchase authentic products then you can easily reap big health benefits.

Lose weight

Apart from all the above benefits, Resveratrol Ultima also aids in weight loss. As you age, it becomes more and more easy to gain pounds. Also, vigorous workouts become difficult due to the increasing weakness in the body.

However, instead of allowing your waistline to expand, you can do something about it. Herbal supplements can help you shed weight in a safe and natural way without any side effects unlike other weight loss products.

No effect on hormones

Most anti aging supplements contain ingredients that can affect your hormones. This can cause more harm than good in most cases. This is because hormonal balance is crucial for the wellbeing of humans. A sudden increase or decrease in hormonal levels can have serious effects in some cases.

Therefore, you want to make sure that any product you take will not affect your hormones.

Improve the condition of your skin

As you start to age, your skin gets affected in the process. It loses elasticity and starts to sag. With the right herbal product, you can easily delay the onset of wrinkles and help replace old skin cells effectively. Once your skin's texture is improved, you will automatically appear more young. Therefore, apart from inner benefits, herbs can also improve your outer appearance.

With all the above anti aging benefits of herbal supplements such as Resveratrol Ultima, there is little reason why you should not go ahead and try them for yourself. Just make sure that you purchase from reliable places so that you can be assured of only authentic products.

Only genuine supplements will provide you with all the benefits mentioned above. So keep that in mind when making a purchase. Afterall, your health is precious.

How To Minimize Wrinkles

We understand it's frustrating: You look in the mirror and see the first signs of fine lines and wrinkles. They're around your eyes, your mouth, even your forehead -- and they're bringing their friends! Depending on how much sun exposure you've had and how well you've protected your skin from sun damage, wrinkles can start showing up as early as your mid-twenties. Regardless of age, the stress you have about your wrinkles can result in lots of money wasted as you try to stop them from getting worse.

Before you can spend your money wisely on products that can truly show you how to minimize wrinkles, you need to know the causes behind what you're really fighting.

What Causes Wrinkles?

How your skin ages and wrinkles is a very complex series of events, but the primary factors include:

1. Sun Damage -- Repeated exposure to the sun or tanning beds destroys collagen, elastin, and produces abnormal skin cells that do not behave like young skin. Sun damage is the major cause of wrinkling. The number one key of how to minimize wrinkles is to stay out of the sun!

2. Genetics -- Your skin color effects how your skin handles sun damage. Darker skin tones are less vulnerable to the sun's impact on skin.

3. Chronological Aging -- As we age the years negatively influence our skin, just as they do for rest of our body.

4. Hormone Loss -- Menopause changes the texture and elasticity of skin. Skin becomes crepey, thinner, and doesn't bounce back when pinched.

5. Fat and Bone Depletion -- Your skin is supported by both fat and bone. As you age, some of that support is lost, which causes skin to sag.

6. Muscle Movement -- The parts of your face you use the most wrinkle the fastest and deepest. Plus, facial muscles lax over time, causing further sagging.

7. Disruption of Skin's Protective Barrier -- Unprotected sun exposure decreases vital substances in skin (such as ceramides and lecithin), leaving your skin more vulnerable to damage by the sun, smoke, and pollution.

What About Collagen?

So, you're at the cosmetics counter inquiring about how to minimize wrinkles and the anti-wrinkle product you're thinking of buying claims it can build collagen, resulting in firmer, less-wrinkled skin. That sounds great, but is it really possible?

Let's put it this way: adding collagen to a skin-care product cannot rebuild collagen! It just isn't possible, no matter what the claims on the label say.

However, your skin does need collagen because it gives your skin its strength, resilience, and structure. It's when the skin's natural collagen becomes damaged by the seven reasons above that wrinkles begin to appear. But, there's a lot you can do to help repair the damage and bring your skin to a healthier, younger-looking state.

Any anti-wrinkle product worth your time and money is one that can help your skin function as younger skin. AND - it takes an entire skin-care routine, not just one product. Well-formulated skin-care products include lots of antioxidants, ingredients that can put back into skin what it has lost, ingredients that help generate normal cells again, and, of course, SUNSCREEN!

Anti-Aging Treatments

As previously noted, many anti-oxidants are essential nutrients. Natural anti-oxidants, like vitamin C and E, work synergistically. Anti-oxidants may be more effective if obtained from a diet rich in fruits and vegetables. Nutritionists recommend eating 6 or more daily servings of anti-oxidant rich fruits and vegetables. Everyone agrees the use of antioxidant supplements for anti-aging may be helpful, but there is no agreement on what the most effective supplement dosages should be.

Anti-aging medicine acknowledges that stress of all kinds causes aging but has not yet developed individualized treatment for this. There are countless sources of internal and external stress and individual stress levels vary greatly. One overlooked cause of internal stress is improper hydration. Water is essential in for the correct operation of many internal functions. Too little or too much water causes age producing stress. When one is old (80+) thirst perception declines and dehydration can easily set in. Other overlooked sources of stress are antioxidants themselves. High doses (or doses above certain yet unspecified amounts) of supplemental anti-oxidants are a known cause of stress.

To be helpful, antioxidant supplements must prevent other types of stress more than the stress they themselves create. Knowing the correct supplement dosages that can do this is an essential part of anti-aging treatment. A healthy young person in his twenties, who is properly nourished, will have less internal stress that an older individual in his sixties. For a young individual, lower amounts of antioxidants may be safer than higher amounts. A older person, whose many internal homeostatic mechanisms are less able to deal with internal stress, may benefit more from higher amounts of antioxidants. Theoretically an anti-oxidant based course of anti-ageing treatment will slow the rate at which cellular damage occurs. Cells will become "sick" more slowly. Over time, as fewer sick cells are replaced at a slower rate, the number of cells retaining longer telomere chains will be higher. You can then reasonably expect this to result in an increase in life expectancy. For now the recommended but imprecise approach to decrease the rate at which cellular damage occurs is to increase your per day intake of anti-oxidant rich fruits and vegetables, to slightly increase your intake of antioxidants, and to take various vitamins and small amounts of anti-aging supplements on a daily basis. One study has shown taking a good multivitamin supplement is associated with longer telomere length.

Ideally anti-aging treatment should to be fine tuned for each individual. The key here would be to measure and minimize the cumulative effects of different kinds of stress on an individual basis. Easily measurable practical bio-markers for various types of stress do not yet exist or are not being used. When they are used it will be easy to customize individual antioxidant dosages so that everyone have "optimum" levels throughout their life. "Optimum" levels would maintain a safe reserve of protective antioxidants in the body.

Next I will briefly discuss the most popular nutrients associated with anti-aging. The most popular of the anti-oxidants, vitamins, and nutrients often associated with good health and anti-aging include: beta-carotene (vitamin A), vitamin C, vitamin E, various Flavonoids,Omega-3 and omega-6 fatty acids, Co-enzyme Q10, Lycopene, Selenium.

There are dozens of supplements that are known to effectively treat specific symptoms of old age. A few of the better known supplements include: DMAE, Acetyl-l-carnitine, L-carnosine, Alpha Lipoic Acid, DHEA, L-arginine, and melatonin

Good food contains some of the anti-oxidants previously mentioned. A few other popular foods associated with anti-aging include: Green Tea, turmeric, and red wine.

All of the above have unique biological properties and, in my opinion, are "good" for you if taken in small or moderate amounts. Some (ex. vitamin C) may also be "good" for you in larger amounts. Various studies on each of these may conflict with each other. You need to carefully research each substance on your own but researchers have already found several nutrients to be associated with longer than average telomere lengths. These include: Green Tea, Omega-3, Vitamins A, C, D, and E.

Vitamin E has been associated with telomere lengthening anti-aging properties.

Green tea contains many antioxidants, including vitamin C, E and flavenoids.Flavenoids form a large antioxidant class (including catechins and quercetin) that has many anticarcinogenic, antihypercholesterolemic, antibacterial, (helps prevent dental caries), and anti-inflammatory properties. The leaves of the tea plant are rich in polyphenols. The consumption of 3 cups or more of green tea daily has been associated with longer than average telomere length.

The Omega-3s are essential long-chain polyunsaturated fatty acids that are anti-inflammatory and help prevent heart disease, stroke, memory loss, depression, arthritis, cataract, cancer. Omega-3s slow down the shortening of telomeres; i.e. they may protect against aging on a cellular level.

Vitamin C is an abundant internal water soluble antioxidant that protects cellular components against free-radical formation caused by pollution and cigarette smoke. Many studies have associated high vitamin C intakes with lower rates of cancer of the mouth, larynx and esophagus. Vitamin C has shown promise in treating premature aging and possibly aging itself.

Due to limitations on the number of links I can incorporate into this article I could not provide more reference links supporting the preceding paragraphs. If interested please email me at the email address shown at the end of this article and I will forward them to you.

The sooner you start some sort of anti-aging treatment the better but it is never too late to start. All real treatments will help you maintain a longer than average average telomere chain length.

The goal of the programmed death theory of aging is to address the root causes of aging. This goal includes attempts to slow or reverse the telomere shortening process. Two such treatments are: TA 65 and human genetic engineering.

TA 65 is a telomerase activating product produced and marketed by Sierra Sciences. The key ingredient in TA 65 is Astragalus, a plant extract known to have telomerase activation properties. The product may work but I do not recommend it for several reasons. TA 65 is too expensive for the average person. A number of expensive health spas incorporate TA 65 in their programs. Again these are financially beyond the reach of the average person. The marketing tactics of Sierra Sciences have been questioned by many and there are law suits pending against TA 65

Human genetic engineering is the real answer to fighting and defeating aging. It can directly address the root causes of aging. Advances in this area (ex. CRISPR) allow DNA base pairs to be inserted or deleted at specific place in our DNA. This means the human genome can now be precisely edited as needed. The lifespan of old mice has been modestly increased using telomerase gene therapy. In humans gene modification therapy has frequently been used for various medical problems. On September 15, 2015, Elizabeth Parrish was the first human to undergo anti-aging gene therapy. Anti-aging treatments will rapidly advance as our knowledge of the specifics of the human genome grows.

Current general social-political attitudes seem to be favoring the further development of anti-aging research. There are no international recognized political programs to stop aging or extend life but since 2012 a few pro-immortality political parties have sprung up. Their aim is to support anti-aging and life extension research, and to help provide access to advances in these areas to everyone. Among the numerous organizations supporting anti-aging research, the SENS (Strategies for Engineered Negligible Senescence) organization has come up with an anti-aging research plan. They want to develop anti-aging therapies to repair most forms of cellular damage. SENS, is a charitable organization. Any anti-aging advances resulting from funding it provides will become readily available public knowledge. In addition to the normal scientific research there is the $1,000,00 Palo Alto Longevity Prize that is being offered to anyone who can come up with an effective anti-aging treatment.

As of 2015, all known anti-aging treatments are only partially effective. Depending on when one starts a comprehensive anti-aging program, one can probably extend one's life by 10 to 25 years. Researchers from the Harvard School of Public Health estimated that an anti-aging lifestyle can add 24.6 more productive years to one's lifespan. Anti-aging knowledge increases at a rate of about 10 times every 10 years. This probably means that for many of us there is more than enough time to reap the anticipated benefits in anti-aging research. One day soon, aging, like many other diseases, will be cured. While we wait for those anti-aging technological singularities to occur the name of the game is to ensure we stay healthy long enough repeat their benefits.

As a former engineer I have a strong affinity to all sciences including biology.
My interests include following advances in the fields of anti-aging, health and nutrition. Rapid advances in these areas will vanquish the disease we call aging.
Through my articles and website I want to help you maintain your good health for the next 10 to 25 years. I believe this can be done by a daily program that includes moderate exercise, a healthy diet that includes vitamins and related supplements, and taking advantage of any advances in related research. My hope is that within the next 25 years or less, the fruits of anti-aging research will become available to everyone.